RewriteEngine On

RewriteRule ^/(typo3|typo3temp|typo3conf|t3lib|tslib|fileadmin|uploads|showpic\.php)$ - [L]
RewriteRule ^/(typo3|typo3temp|typo3conf|t3lib|tslib|fileadmin|uploads|showpic\.php)/.*$ - [L]

RewriteCond %{REQUEST_FILENAME} !-f
RewriteCond %{REQUEST_FILENAME} !-d
RewriteCond %{REQUEST_FILENAME} !-l
RewriteRule .* index.php